5th wheel
There is a hitch (Pull-Rite) which moves the pivot point of a regular trailer to the rear axel point, so the towing differences are minimized.
If you have a pickup truck, you can pull either a 5th wheel or travel trailer. If you have any other truck (SUV, van) you can only pull a travel trailer.
5th wheels tend to be taller than travel trailers, a factor if you are tall, at the cost of greater wind resistance, side wind sensitivity and damage from low obsticles. Also, there is a steep staircase up to the part of the trailer (often the bedroom) which is over the truck bed. And that portion of the floor plan is usually does not have much interior height (because it has to clear the truck bed). Travel trailers are all the same level and mostly the same interior height.
Of course, your overall length with a 5th wheel is less for the same floor size, since some of it overlaps the truck length. Also, 5th wheels seem to have more storage than travel trailers.